Adicet Bio is a clinical-stage biotechnology company developing allogeneic gamma delta T cell therapies for autoimmune diseases and cancer. The company's approach involves engineering gamma delta T cells with chimeric antigen receptors (CARs) to create off-the-shelf cellular therapies. This allogeneic model distinguishes Adicet's platform from autologous CAR-T approaches, potentially enabling standardized manufacturing and broader patient access.
The company's lead candidate, ADI-001, is an allogeneic gamma delta CAR-T cell therapy targeting CD20, currently in Phase I clinical development for autoimmune diseases and relapsed/refractory B-cell non-Hodgkin's lymphoma. ADI-270, a second program, represents an armored gamma delta CAR-T cell candidate designed to address CD70-positive solid tumors and hematological malignancies, with renal cell carcinoma as an initial indication.
Adicet Bio operates as a private development-stage entity with no disclosed revenue streams. The company maintains a workforce of approximately 152 full-time employees and is headquartered in Boston, Massachusetts. The organization was founded in 2014 and incorporated in Delaware.
Fiscal years are as reported by the company and may not align with the calendar year. For example, Apple's FY 2024 ends in September 2024.
| Fiscal Year | EPS Diluted | EPS Basic | YoY | |
|---|---|---|---|---|
| 2024 | $-1.33 | $-1.33 | +59.8% | |
| 2023 | $-3.31 | $-3.31 | -94.7% | |
| 2022 | $-1.70 | $-1.70 | — | |
| 2021 | — | — | — | |
| 2020 | — | — | — | |
| 2019 | — | — | — | |
| 2018 | — | — | — |
| Report Date | Filed | Accession Number | |
|---|---|---|---|
| 2024-12-31 | 2025-03-06 | 0000950170-25-034587 | SEC ↗ |
| 2023-12-31 | 2024-03-19 | 0000950170-24-033482 | SEC ↗ |
| 2022-12-31 | 2023-03-15 | 0000950170-23-008130 | SEC ↗ |
| 2021-12-31 | 2022-03-15 | 0000950170-22-003753 | SEC ↗ |
| 2020-12-31 | 2021-03-12 | 0001564590-21-012664 | SEC ↗ |
| 2019-12-31 | 2020-03-12 | 0001564590-20-010474 | SEC ↗ |
| 2018-12-31 | 2019-03-18 | 0001564590-19-008262 | SEC ↗ |
| 2017-12-31 | 2018-03-29 | 0001564590-18-007150 | SEC ↗ |