SMMT · CIK 0001599298 · operating
Summit Therapeutics is a biopharmaceutical company engaged in the discovery, development, and commercialization of therapeutic medicines. The company's primary focus is its lead development candidate, ivonescimab, a bispecific antibody that combines PD-1 blockade with anti-angiogenic properties for treating solid tumors. Ivonescimab is currently in phase III clinical trials across multiple indications, including first-line treatment of metastatic non-small cell lung cancer (NSCLC) in patients with epidermal growth factor receptor mutations, first-line metastatic NSCLC, and first-line unresectable metastatic colorectal cancer. The company is also evaluating ivonescimab in combination with chemotherapy across these same indications.
Summit Therapeutics operates with approximately 265 full-time employees and maintains its headquarters in Miami, Florida. The company has established a geographic footprint spanning North America, Europe, Asia-Pacific, Latin America, and the Middle East and Africa regions to support its clinical development and commercialization activities. Founded in 2003, the company is listed on Nasdaq with a market capitalization of $12.4 billion, reflecting investor interest in its immunotherapy pipeline and the commercial potential of its bispecific antibody platform.
Fiscal years are as reported by the company and may not align with the calendar year. For example, Apple's FY 2024 ends in September 2024.
| Fiscal Year | EPS Diluted | EPS Basic | YoY | |
|---|---|---|---|---|
| 2025 | $-1.44 | $-1.44 | -364.5% | |
| 2024 | $-0.31 | $-0.31 | +68.7% | |
| 2023 | $-0.99 | $-0.99 | -141.5% | |
| 2022 | $-0.41 | $-0.41 | +57.3% | |
| 2021 | $-0.96 | $-0.96 | -26.3% | |
| 2020 | $-0.76 | $-0.76 | — |
| Report Date | Filed | Accession Number | |
|---|---|---|---|
| 2025-12-31 | 2026-02-23 | 0001599298-26-000015 | SEC ↗ |
| 2024-12-31 | 2025-02-24 | 0001599298-25-000048 | SEC ↗ |
| 2023-12-31 | 2024-02-20 | 0001599298-24-000031 | SEC ↗ |
| 2022-12-31 | 2023-03-09 | 0001599298-23-000034 | SEC ↗ |
| 2021-12-31 | 2022-03-17 | 0001599298-22-000032 | SEC ↗ |
| 2020-12-31 | 2021-03-31 | 0001599298-21-000011 | SEC ↗ |